TY - JOUR AU - Hardi, Hidayu Permata AU - Soerohardjo, Indrawarman AU - Hendri, Ahmad Zulfan PY - 2023/04/05 Y2 - 2024/03/28 TI - Analysis of hematological parameters in bladder cancer in early and advanced stages at Dr. Sardjito Hospital JF - JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JA - JKKI VL - 14 IS - 1 SE - Original Article DO - 10.20885/JKKI.Vol14.Iss1.art2 UR - https://journal.uii.ac.id/JKKI/article/view/25179 SP - 3-8 AB - <p>Background: Bladder cancer (BC) is the tenth most common cancer in both males and females. Early detection can improve the patient's chances of survival, giving patients with BC a good prognosis. The hematological parameter determines the number of leukocytes, hemoglobin, platelets, and Neutrophil-Lymphocyte Ratio (NLR) in the body. The presence of abnormal values on hematological parameters indicates that the patient is in poor condition.<br />Objective: This study aims to compare hematological parameters between early-stage and advanced BC at Dr. Sardjito Hospital.<br />Methods: This study was a retrospective cross-sectional study using patient medical records. By using the results of the anatomical pathology, pre-operative hematology evaluated the influence on the bladder cancer stage. The sample used consisted of 130 bladder cancer patients. Chi-square and regression statistical tests were used to analyze the collected data.<br />Results: The advanced-stage group had considerably higher leukocytosis than the early-stage group (p = 0.000). Anemia predominated more in the later-stage group than in the earlier stage (p = 0.048). Additionally, the advanced-stage group experienced thrombocytosis more frequently than the early-stage group (p = 0.000). NLR was higher in the advanced compared to the early-stage group (p = 0.000).<br />Conclusion: Patients with advanced bladder cancer were more likely to experience abnormal hematological parameters levels than those with the earliest stages of the disease.</p> ER -