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Abstract
Solvent extraction of dog rose seed was conducted to establish best operation conditions for future study. Extraction variables were temperature, solvent type and L/S ratio. The best extraction conditions at laboratory scale were investigated applying Box-Behnken design (BBD) using response surface methodology (RSM). The highest extract yield was obtained (6.93 %) by isopropanol at the optimum conditions of 3 L/S ratio and 50-55 0C temperature range. Results of experiments confirmed the results of prediction.
Keywords
extraction conditions
solvent ratio
response surface methodology
solvent type
optimum conditions