Main Article Content
Abstract
ABSTRACT
Two resveratrol tetramers, (-)-vaticanol B and (-)-hopeaphenol, were isolated from acetone
extract of the tree bark of Dipterocarpus hasseltii (Dipterocarpaceae), together with the known
resveratrol trimer, (-)-α-viniferin. The structures of these compounds were established based on
spectroscopic evidence, UV, IR,
1
H-NMR,
13
C-NMR and determined by comparison with the
standard compounds. The cytotoxic activities of these compounds were evaluated against murine
leukaemia P-388 cells. The IC50 values of all compounds were 42.2, 5.0 and 17.5 μg/ml,
respectively. In addition, chemotaxonomic significance relationship between Dipterocarpus, Shorea
and Vatica will also be briefly discussed.
Keywords: Chemotaxonomy, Cytotoxic, Dipterocarpaceae, D. hasseltii,Resveratrol
tetramer
Article Details
Authors who publish in the Jurnal Ilmiah Farmasi agree to the following terms:
- Authors retain copyright and grant Jurnal Ilmiah Farmasi right of first publication with the work simultaneously licensed under a Creative Commons Attribution Licence that allows others to adapt (remix, transform, and build) upon the work non-commercially with an acknowledgement of the work's authorship and initial publication in Jurnal Ilmiah Farmasi.
- Authors are permitted to share (copy and redistribute) the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in Jurnal Ilmiah Farmasi.