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Abstract
ABSTRACT
It is well know that adipose tissue mass increase greatly in obesity. In Indonesia obesity
prevalence tends to increase. It raised the risk of morbidity and total cost attributable to obesity
related disease. The adipose tissue is energy storage, fatty acids being released when fuel is
required. It is now adipose tissue expresses and secretes factors with impotant endicrine functions.
These factor include adiponectin, adipsin, leptin, protein of the renin-angiotensin system,
plasminogen activator-1, other cytokines and resistin. A better understanding of the endocrine
function of adipose tissue will give evidence of links between increased productios of some
adipocyte factors and the metabolic and cardiovascular complications of obesity.
Key words: adipose tissue, obesity, endocrine organ