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Abstract

ABSTRACT
The latest discoveries in the field of microbiology have proved that bacteria communicate each
other. The process of cell to cell communication is called quorum sensing. Quorum sensing was
first discovered in two luminous bacteria called Vibrio harveyi and Vibrio fischeri. These bacteria
emit light in response to increase in cell population density. Density-dependent light production is
accomplished trough the release and detection of hormone-like molecules called autoinducers that
accumulate in the environment as the bacterial density increases. Quorum sensing is believed to
regulate competence in development, sporulation, virulence factor induction, sporulation and
nutrient flux along with other events in pathogenic bacterial infections. Recently, many scientist
have been doing research in the field of quorum sensing. If the signaling systems among the
bacteria were able to be blocked, the dangerous effects from bacteria then possibly be prevented.
In other word, if the quorum sensing mechanism were stopped, the disease can be prevented or
even cured instead of antibiotics use.

Keyword : bacterial infection – quorum sensing - inhibiton

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