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Abstract
Background: The manifestation of dengue is a decrease in hematocrit and platelet levels, leading to a decrease in the patient’s quality of life and having an impact on the patient’s medical costs.
Objective: This study objective was to ascertain the quality of life and medical costs associated with dengue patients.
Method: This study employed a cross-sectional design at PKU Muhammadiyah Hospitals in Bantul and Yogyakarta from January to August in 2023. Pediatric patients’ quality of life was assessed using the EQ-5D-Y questionnaire, while adult patients’ using the EQ-5D-5L questionnaire. Data on patients’ medical costs was obtained from the hospital's financial database. The data were then analyzed descriptively and presented as a percentage of quality of life and average medical costs.
Results: The results showed that pediatric DF patients in both hospitals reported anxiety and depression, with percentages of 100% (Yogyakarta) and 75% (Bantul), respectively. Meanwhile, most adult DF patients experienced problems in carrying out routines, 71.4% (Yogyakarta) and 50% (Bantul), respectively. Adult DHF patients in both hospitals reported pain and discomfort of 66.7% (Yogyakarta) and 100% (Bantul), respectively. The highest average medical costs paid by DF and DHF patients at PKU Jogja Hospital were IDR 4,919,450 and IDR 6,981,500. DF and DHF patients at PKU Hospital with BPJS insurance, with the highest average medical costs of IDR 2,726,245.5 (for DF patients) and IDR 4,797,700 (for DHF patients) to cover for laboratory costs.
Conclusion: Dengue fever infections are impacting the patient's quality of life and medical costs.
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References
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References
Amini, N. H., Hartoyo, E., & Rahmiati. (2019). Hubungan Hematokrit dan Jumlah Trombosit Terhadap Lama Rawat Inap Pasien DBD Anak Di RSUD Ulin Banjarmasin. Jurnal Homeostasis, 2(3), 407–416.
Carrington L.B. & Simmons C.P. (2014). Human to Mosquito Transmission of Dengue Viruses. Frontiers in Immunology, 17(5), 1-8. https://doi.org/10.3389/fimmu.2014.00290.
Dinkes DIY. (2021). Profil Kesehatan D.I. Yogyakarta Tahun 2020. Dinas Kesehatan Provinsi Daerah Istimewa Yogtakarta. Yogyakarta: Dinas Kesehatan Daerah Istimewa Yogyakarta.
Dwi, R., Dan, W., & Sabir, M. (2011). Karakteristik Penderita Demam Berdarah Dengue (DBD) di Rumah Sakit Wahidin Sudirohusodo Makassar Periode Januari-Desember 2010. Inspirasi, 1(14), 1-24.
Halasa, Y. A., Shepard, D. S., & Zeng, W. (2012). Economic cost of dengue in Puerto Rico. American Journal of Tropical Medicine and Hygiene, 86(5), 745–752. https://doi.org/10.4269/ajtmh.2012.11-0784
Islammia, D.P.A., Rumana, N. A., Indawati, L., & Dewi, D. R. (2022). Karakteristik Pasien Demam Berdarah Dengue Rawat Inap di Rumah Sakit Umum UKI Tahun 2020. SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat, 1(1), 60–70. https://doi.org/10.55123/sehatmas.v1i1.37
Kemenkes RI. (2013) Pedoman Penerapan Kajian Farmakoekonomi. Direktorat Jenderal Bina Kefarmasian dan Alat Kesehatan. Jakarta: Kementerian Kesehatan Republik Indonesia.
Kemenkes RI (2020). Pedoman Nasional Pelayanan Kedokteran Tata Laksana Infeksi Dengue pada Pasien Dewasa. Jakarta: Kementerian Kesehatan Republik Indonesia.
Kemenkes RI (2021). Informasi Singkat DBD 2021 Germas. Jakarta: Kementerian Kesehatan Republik Indonesia.
Kemenkes RI (2023). Informasi Dengue 2023. Jakarta: Kementerian Kesehatan Republik Indonesia.
Lee, J. S., Mogasale, V., Lim, J. K., Carabali, M., Sirivichayakul, C., Anh, D. D., Lee, K. S., Thiem, V. D., Limkittikul, K., Tho, L. H., Velez, I. D., Osorio, J. E., Chanthavanich, P., da Silva, L. J., & Maskery, B. A. (2015). A multi-country study of the household willingness-to-pay for dengue vaccines: Household surveys in Vietnam, Thailand, and Colombia. PLoS Neglected Tropical Diseases, 9(6), 1–15. https://doi.org/10.1371/journal.pntd.0003810
Martelli, C. M. T., Nascimento, N. E., Suaya, J. A., Siqueira, J. B., Souza, W. V., Turchi, M. D., Guilarde, A. O., Peres, J. B., & Shepard, D. S. (2011). Quality of life among adults with confirmed dengue in Brazil. American Journal of Tropical Medicine and Hygiene, 85(4), 732–738. https://doi.org/10.4269/ajtmh.2011.11-0067
Nadjib, M. (2019). The Economic Burden of Dengue in Indonesia. International Pest Control, 61(2), 90–91. https://doi.org/10.1371/journal.pntd.0007038
Prasetyani, D. R. (2015). Faktor-Faktor Yang berhubungan Dengan Kejadian Demam Berdarah Dengue. Majority., 4(7).
Ramadani, F., Azizah, N., Ayu, S. M., & Lubis, T. T. (2023). Hubungan Karakteristik Penderita Demam Berdarah Dengue di Rumah Sakit Haji Medan Periode Januari-Juni 2022. Jurnal Kedokteran dan Kesehatan-Fakultas Kedokteran Universitas Islam Sumatera Utara, 22(2), 189-195. https://doi.org/10.30743/ibnusina.v22i2.498
Ratnawiningsih, H., Perwitasari, D. A., Supadmi, W., & Faridah, I. N. (2022). Kualitas Hidup dan Biaya Sakit Pasien Dengue di Rumah Sakit PKU Muhammadiyah Bantul Yogyakarta. Majalah Farmaseutik, 18(1), 1-7. https://doi.org/10.22146/farmaseutik.v18i1.70539
Rohman, H., & Susilowati, E. (2020). Analisis Perbedaan Biaya Pasien Demam Berdarah Dengue dengan dan Tanpa Clinical Pathway di Rumah Sakit Condong Catur. Prosiding: Seminar Manajemen Informasi Kesehatan Nasional dan Call for Paper, 47–53.
Sari, A., Yuni Lestari, N., & Aryani Perwitasari, D. (2015). Validasi ST European Quality OF Life-5 Dimensions (EQ-5D) Versi Indonesia Pada Pasien Hipertensi Di Puskesmas Kotagede II Yogyakarta. Pharmaciana, 5(2). https://doi.org/10.12928/pharmaciana.v5i2.2483
Sihite, E. W., Mahendradata, Y., & Baskoro, T. (2017). Beban Biaya Penyakit Demam Berdarah Dengue di Rumah Sakit dan Puskesmas Cost Burden of Dengue Hemorrhagic Fever in Hospitals and Public Health Centers. Berita Kedokteran Masyarakat (BKM Journal of Community Medicine and Public Health, 33(7), 375–364. https://doi.org/10.22146/bkm.13699
Sumaryati, M., Rosmiati, & Wasilah. (2019). Studi Kasus pada Pasien Demam Berdarah Dengue. Jurnal Ilmiah Kesehatan Sandi Husada, 10(2), 51-56. https://doi.org/10.35816/jiskh.v10i2.106
van Reenen, M., Janssen, B., Oppe, M., Kreimeier, S., Greiner, W., Stolk, E., Secnik Boye, K., Herdman, M., Kennedy-Martin, M., Kennedy-Martin, T., & Slaap, B. (2015). CHANGES INCLUDED in this update of the EQ-5D-Y User Guide Table of contents: Vol. 2.1 (2nd ed.). EuroQol Research Foundation. Available from www.euroqol.org
van Reenen, M. V., Janssen, B., Stolk, E., Boye, K. S., Herdman, M., Kennedy-Martin, M., Kennedy-Martin, T., & Slaap, B. (2019). EQ-5D User Guide Basic Information on How to Use the EQ-5D-5L Instrument Version 3.0. The Netherland: EueoQol Research Foundation, 36.
WHO. (2011). Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Hemorrhagic Fever. World Health Organization Regional Office for South-East Asia.
WHO. (2023). Dengue and Severe Dengue. World Health Organization.
Wilastonegoro, N. N., Kharisma, D. D., Laksono, I. S., Halasa-Rappel, Y. A., Brady, O. J., & Shepard, D. S. (2020). Cost of Dengue Illness in Indonesia Across Hospital, Ambulatory, and not Medically Attended Settings. American Journal of Tropical Medicine and Hygiene, 103(5), 2029–2039. https://doi.org/10.4269/ajtmh.19-0855