Main Article Content
Abstract
Background: Iron Deficiency Anaemia (IDA) is one of major factors for human health, especially young children. Iron supplementation can indicate a good response in haemoglobin concentration.
Objective: This study is to observe prevalence of anaemia and effectiveness of iron supplementation for children in Purbalingga district, Central Java.
Methods: This study was a quasi-experimental study by measuring haemoglobin concentration before (pre) and after (post) treatment. Its participants were determined by a purposive sampling method. 64 children (less than 5 years old) were included in criteria of anaemia. Their blood samples were collected before the treatment to measure SI (Serum Iron) and TIBC (Total Iron Binding Capacity). Administering 4 mg of iron per kg of body weight per day was conducted for a month. Data of participants such as age, nutritional status, socio-demographic, and medical history were also collected. A paired t-test was used to analyse mean differences of haemoglobin levels before and after treatment.
Results: Among the 64 children with anaemia, 98.4% indicated Iron Deficiency (ID) with 59.4% of them indicating IDA based on level of SI and TIBC. Anaemia has more prevalence in group of 6 - <12 months of age. There was a statistically significant increase of haemoglobin level with a mean difference of 1.52 g/dL between the pre and post treatment (p=0.000).
Conclusion: The prevalence of IDA in children (less than 5 years old) in Purbalingga District Hospital was 59.4%. Adequately oral iron supplementation for a month indicated a statistically significant increase of haemoglobin levels
Keywords
Article Details
Authors who publish in the Jurnal Kedokteran dan Kesehatan Indonesia agree to the following terms:
- Authors retain copyright and grant Jurnal Kedokteran dan Kesehatan Indonesia right of first publication with the work simultaneously licensed under a Creative Commons Attribution Licence that allows others to adapt (remix, transform, and build) upon the work non-commercially with an acknowledgement of the work's authorship and initial publication in Jurnal Kedokteran dan Kesehatan Indonesia.
- Authors are permitted to share (copy and redistribute) the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in Jurnal Kedokteran dan Kesehatan Indonesia.
References
- Kementrian Kesehatan RI. Profil Kesehatan Indonesia Tahun 2013. Jakarta: Sekretariat Jendral Departement Kesehatan. 2014.
- Statistic Indonesia (Badan Pusat Statistik-BPS), National Population and Family Planning Board (BKKBN, Kementerian Kesehatan (Kemenkes-MOH)) and ICF International. Indonesia demographic and health survey 2012. Jakarta: BPS, BKKBN, Kemenkes, and ICF International. 2013.
- Indonesia Ministry of Health General Secretariat. Indonesia health profile 2018. Jakarta: Ministry of Health RI. 2018.
- De Pee S, Bloem MW, Sari M, Kiess L, Yip R, Kosen S. The high prevalence of low hemoglobin concentration among Indonesian infants aged 3–5 months is related to maternal anemia. The Journal of Nutrition. 2002;132(8):2215–21.
- Baker RD, Greer FR, Bhatia JJS, Abrams SA, Daniels SR, Schneider MB, et al. Clinical report - diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age). Pediatrics. 2010;126(5):1040–50.
- Metallinos-Katsaras E, Valassi-Adam E, Dewey KG, Lönnerdal B, Stamoulakatou A, Pollitt E. Effect of iron supplementation on cognition in Greek preschoolers. European Journal of Clinical Nutrition. 2004;58(11):1532–42.
- Soewondo S. The effect of iron deficiency and mental stimulation on Indonesian children’s cognitive performance and development. Kobe Journal of Medical Sciences. 1995;41(1–2):1–17.
- Kordas K, Lopez P, Rosado JL, García Vargas G, Alatorre Rico J, Ronquillo D, et al. Blood lead, anemia, and short stature are independently associated with cognitive performance in Mexican school children. The Journal of Nutrition. 2004;134(2):363–71.
- Cherayil BJ. Iron and immunity: Immunological consequences of iron deficiency and overload. Archivum Immunologiae et Therapiae Experimentalis. 2010;58(6):407–15.
- Soemantri AG, Pollitt E, Kim I. Iron deficiency anemia and educational achievement. American Journal of Clinical Nutrition. 1985;42(6):1221–8.
- Muhilal, Suharno D, Saidin S, Permaesih D, Satibi I. Iron supplementation pilot programme. Gizi Indonesia. 1985;30–4.
- Pudjiadi AH, Hegar B, Handryastuti S, Idris NS, Gandaputra EP, Harmoniati ED, editors. Anemia defisiensi besi. In: pedoman pelayanan medis ikatan dokter anak Indonesia. Jakarta: IDAI; 2009. p. 10–3.
- Riyanto Widjaja I, Firyanto Widjaja F, Alim Santoso L, Wonggokusuma, E, Oktaviati O. Anemia among children and adolescents in a rural area. Paediatrica Indonesiana. 2013;54(2):88–93.
- Widiaskara I, Pramitha P, Suryawan IWB, Ugrasena I. Gambaran hematologi anemia defisiensi besi pada anak. Sari Pediatri. 2016;13(5):362.
- WHO. Guideline daily iron supplementation in infants and children. Geneva: World Health Organization. 2016;44.
- Muhammad A, Sianipar O. Determination of iron deficiency in chronic disease anemia by the role of sTfR-F index. Indonesian Journal of Clinical Pathology and Medical Laboratory. 2005;12(1):9–15.
- Permono B, Sutaryo UIDG, Windiastuti E, Abdulsalam M. Buku ajar hematologi-onkologi anak. Jakarta: Badan Penerbit Ikatan Dokter Anak Indonesia; 2017.
- Cotta RMM, Fabiana de Cássia Carvalho Oliveira, Magalhães KA, Ribeiro AQ, Sant’Ana LF da R, Priore SE, et al. Social and biological determinants of iron deficiency anemia. Cadernos de Saúde Pública. 2011;27(suppl 2):s309–20.
- Sjarif DR, Yuliarti K, Lestari ED, Sidiartha IGL, Nasar SS, Mexitalia M. Rekomendasi praktik pemberian makan berbasis bukti pada bayi dan balita di Indonesia untuk mencegah malnutrisi. Jakarta: Ikatan Dokter Anak Indonesia. 2015;
References
Kementrian Kesehatan RI. Profil Kesehatan Indonesia Tahun 2013. Jakarta: Sekretariat Jendral Departement Kesehatan. 2014.
Statistic Indonesia (Badan Pusat Statistik-BPS), National Population and Family Planning Board (BKKBN, Kementerian Kesehatan (Kemenkes-MOH)) and ICF International. Indonesia demographic and health survey 2012. Jakarta: BPS, BKKBN, Kemenkes, and ICF International. 2013.
Indonesia Ministry of Health General Secretariat. Indonesia health profile 2018. Jakarta: Ministry of Health RI. 2018.
De Pee S, Bloem MW, Sari M, Kiess L, Yip R, Kosen S. The high prevalence of low hemoglobin concentration among Indonesian infants aged 3–5 months is related to maternal anemia. The Journal of Nutrition. 2002;132(8):2215–21.
Baker RD, Greer FR, Bhatia JJS, Abrams SA, Daniels SR, Schneider MB, et al. Clinical report - diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age). Pediatrics. 2010;126(5):1040–50.
Metallinos-Katsaras E, Valassi-Adam E, Dewey KG, Lönnerdal B, Stamoulakatou A, Pollitt E. Effect of iron supplementation on cognition in Greek preschoolers. European Journal of Clinical Nutrition. 2004;58(11):1532–42.
Soewondo S. The effect of iron deficiency and mental stimulation on Indonesian children’s cognitive performance and development. Kobe Journal of Medical Sciences. 1995;41(1–2):1–17.
Kordas K, Lopez P, Rosado JL, García Vargas G, Alatorre Rico J, Ronquillo D, et al. Blood lead, anemia, and short stature are independently associated with cognitive performance in Mexican school children. The Journal of Nutrition. 2004;134(2):363–71.
Cherayil BJ. Iron and immunity: Immunological consequences of iron deficiency and overload. Archivum Immunologiae et Therapiae Experimentalis. 2010;58(6):407–15.
Soemantri AG, Pollitt E, Kim I. Iron deficiency anemia and educational achievement. American Journal of Clinical Nutrition. 1985;42(6):1221–8.
Muhilal, Suharno D, Saidin S, Permaesih D, Satibi I. Iron supplementation pilot programme. Gizi Indonesia. 1985;30–4.
Pudjiadi AH, Hegar B, Handryastuti S, Idris NS, Gandaputra EP, Harmoniati ED, editors. Anemia defisiensi besi. In: pedoman pelayanan medis ikatan dokter anak Indonesia. Jakarta: IDAI; 2009. p. 10–3.
Riyanto Widjaja I, Firyanto Widjaja F, Alim Santoso L, Wonggokusuma, E, Oktaviati O. Anemia among children and adolescents in a rural area. Paediatrica Indonesiana. 2013;54(2):88–93.
Widiaskara I, Pramitha P, Suryawan IWB, Ugrasena I. Gambaran hematologi anemia defisiensi besi pada anak. Sari Pediatri. 2016;13(5):362.
WHO. Guideline daily iron supplementation in infants and children. Geneva: World Health Organization. 2016;44.
Muhammad A, Sianipar O. Determination of iron deficiency in chronic disease anemia by the role of sTfR-F index. Indonesian Journal of Clinical Pathology and Medical Laboratory. 2005;12(1):9–15.
Permono B, Sutaryo UIDG, Windiastuti E, Abdulsalam M. Buku ajar hematologi-onkologi anak. Jakarta: Badan Penerbit Ikatan Dokter Anak Indonesia; 2017.
Cotta RMM, Fabiana de Cássia Carvalho Oliveira, Magalhães KA, Ribeiro AQ, Sant’Ana LF da R, Priore SE, et al. Social and biological determinants of iron deficiency anemia. Cadernos de Saúde Pública. 2011;27(suppl 2):s309–20.
Sjarif DR, Yuliarti K, Lestari ED, Sidiartha IGL, Nasar SS, Mexitalia M. Rekomendasi praktik pemberian makan berbasis bukti pada bayi dan balita di Indonesia untuk mencegah malnutrisi. Jakarta: Ikatan Dokter Anak Indonesia. 2015;