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Submitted
July 2, 2021
Accepted
December 9, 2021
Published
December 31, 2021
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Abstract

Background: The COVID-19 virus has spread throughout the world and has been declared as a global pandemic by WHO. Some population groups are more susceptible to COVID-19, and one of them is pregnant women. Pregnancy increases risks of the COVID-19, especially thrombotic complications. The SARS-CoV-2 infection may vary widely from asymptomatic to severe infection. Some studies have shown that ABO blood group can be a marker of susceptibility to some disease progression.
Objective:This study aims to investigate relationships between the ABO blood group, the COVID-19 infection and its complications in pregnant women at Dr. Moewardi Hospital, Surakarta.
Methods: This study was an observational analytic study with a cross-sectional study design involving 40 pregnant women infected with COVID-19 at Dr. Moewardi Hospital, Surakarta. COVID-19 PCR swabs on the women were administered on their oropharynx and nasopharynx, and laboratory examination of the ABO blood group in all samples was performed. Comparative data distribution of blood groups in the population and the global population distribution were calculated by Chi Square Goodness of Fit. Comparative data between ABO blood group distributions, blood parameters and complications (respiratory, thrombotic, other infections, and death) were calculated by Chi square test and then by One-Way ANOVA. Next, correlation tests for the complications of the blood group and the ages applied a multinomial regression.
Results: There were significant differences of thrombotic complications on the blood group of pregnant women infected with COVID-19 (p=0.027). Blood type B significantly tended to experience thrombotic complications when compared to other blood groups (p=0.022).
Conclusion: The ABO blood group could affect the complication levels in the pregnant women infected with the COVID 19.

Keywords

ABO blood group pregnancy COVID-19

Article Details

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Author Biographies

Sri Sulistyowati, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Marety/Universitas Sebelas Maret Hospital, Surakarta

Obstetrics and dan Gynekology Department UNS Hospital/ Medical Faculty Sebelas Maret University

Nutria Widya Purna Anggraini, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta

Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia

Soetrisno Soetrisno, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Universitas Sebelas Maret Hospital, Surakarta

Obstetrics and  Gynekology Department UNSi Hospital

universitas sebelas maret

Eric Edwin Yuliantara, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta

Obstetrics and  Gynekology Department UNSi Hospital

universitas sebelas maret

Supriyadi Hari Respati, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta

Obstetrics and dan Gynekology Department Dr Moewardi Hospital/

Muhammad Adrianes Bachnas, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta

Obstetrics and dan Gynekology Department Dr Moewardi Hospital/

Wisnu Prabowo, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta

Obstetrics and dan Gynekology Department Dr Moewardi Hospital

Hafi Nurinasari, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Universitas Sebelas Maret Hospital, Surakarta

Obstetrics and dan Gynekology Department Dr Moewardi Hospital/

Dympna Pramelita, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Universitas Sebelas Maret Hospital, Surakarta

Obstetrics and dan Gynekology Department Dr Moewardi Hospital/

Dewi Setiyawati, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Universitas Sebelas Maret Hospital, Surakarta

Obstetrics and dan Gynekology Department Dr Moewardi Hospital/

Metharisa Sujana, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Universitas Sebelas Maret Hospital, Surakarta

Obstetrics and dan Gynekology Department Dr Moewardi Hospital/

Aldi Firmansyah, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sebelas Maret/Universitas Sebelas Maret Hospital, Surakarta

Obstetrics and dan Gynekology Department Dr Moewardi Hospital/

How to Cite
Sulistyowati, S., Anggraini, N. W. P., Soetrisno, S., Yuliantara, E. E., Respati, S. H., Bachnas, M. A., Prabowo, W., Nurinasari, H., Pramelita, D., Setiyawati, D., Sujana, M., & Firmansyah, A. (2021). The effect of ABO blood group on COVID-19 in pregnancy. JKKI : Jurnal Kedokteran Dan Kesehatan Indonesia, 12(3), 233–241. https://doi.org/10.20885/JKKI.Vol12.Iss3.art6
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