Article Sidebar

Submitted
February 6, 2018
Accepted
August 30, 2018
Published
August 30, 2018
Download
PDF Formulir Copy Right Cover Letter COI_disclosure Approval Letter No Plagiarism Authenticity letter
Statistic
Read Counter : 553 Download : 1029

Main Article Content

Abstract

Background: Epilepsy is one of the causing factors of cognitive impairment which affects the patient’s quality of life. The most critical risk factor for cognitive impairment in epilepsy patients is the onset of seizure. Performing detection of cognitive impairment in those patients is crucial. Clock Drawing Test (CDT) is a validated instrument for the detection of cognitive impairment in epilepsy patients.

Objective: This study was aimed to investigate the effect of the onset of seizure on CDT score in epilepsy patients.

Methods: This study was a cross-sectional study involving 64 epilepsy patients of Mutiara Sukma Mental Hospital, West Nusa Tenggara, who met the inclusion but not exclusion criteria. The clinical and demographic characteristics data collected in this study were age, gender, type of seizure, etiology, length of education, duration of treatment, and antiepileptic drugs (AED). Cognitive function evaluation has been done by using the CDT instrument. Analysis of the effect of the beginning of seizure on CDT score was carried out by observing the influence of the clinical and demographic characteristics data.

Results: There was a significant difference between the onset of seizure on CDT score (p<0.05). There were significant differences in aetiology and age in both groups of onsets of the seizure (p <0.05), but not in the characteristics of gender, type of seizure, level of education, duration of treatment and AED in both groups of onsets of the seizure (p>0.05).

Conclusion: The onset of the seizure in epilepsy patients affect CDT score. This effect might be attributed to etiology and age of epilepsy patients.

Keywords

epilepsy cognitive function seizure onset CDT

Article Details

License

Authors who publish in the Jurnal Kedokteran dan Kesehatan Indonesia agree to the following terms:

  1. Authors retain copyright and grant Jurnal Kedokteran dan Kesehatan Indonesia right of first publication with the work simultaneously licensed under a Creative Commons Attribution Licence that allows others to adapt (remix, transform, and build) upon the work non-commercially with an acknowledgement of the work's authorship and initial publication in Jurnal Kedokteran dan Kesehatan Indonesia.
  2. Authors are permitted to share (copy and redistribute) the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in Jurnal Kedokteran dan Kesehatan Indonesia.
Author Biography

Baiq Kania Kartika Yaksa, Student of Program of Doctor, Universitas Mataram, Mataram, Indonesia

Medical Faculty of Mataram University is A grade and always try to make batter.
How to Cite
Yaksa, B. K. K., Harahap, H. S., Amalia, E., & Indrayana, Y. (2018). The effect of the onset of seizure on clock drawing test score of epilepsy patients. JKKI : Jurnal Kedokteran Dan Kesehatan Indonesia, 9(2), 95–101. https://doi.org/10.20885/JKKI.Vol9.Iss2.art6
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. WHO. Epilepsy.[Internet]. 2017 [updated 2017 Feb]. Available from: http://www.who.int/mediacentre/factsheets/fs999/en/
  2. Suwarba IGNM. Insidens dan karakteristik klinis epilepsi pada anak. Sari Pediatri. 2011;13(2).
  3. Harahap HS, Indrayana Y, Amalia E. Treatment pattern and cognitive function in epilepsy patients in Mutiara Sukma Mental Hospital. Jurnal Kedokteran Brawijaya. 2017;29(4):335–40.
  4. Sherwood L.Fisiologi Manusia: Dari sel ke sistem.6thEd.Translated from English by B.U. Pendit.Jakarta: EGC.2011.
  5. Lodhi S and Agrawal N.Neurocognitive problems in epilepsy.Advances in Psychiatric Treatment.2012;18(3):232–240.
  6. Lopes AF, Simões MR, Monteiro JP, Fonseca MJ, Martins C, Ventosa L, et al. Intellectual functioning in children with epilepsy: Frontal lobe epilepsy, childhood absence epilepsy and benign epilepsy with centro-temporal spikes. Seizure [Internet]. BEA Trading Ltd; 2013;22(10):886–92.
  7. Marini C, King MA, Archer JS, Newton MR, Berkovic SF. Idiopathic generalised epilepsy of adult onset: clinical syndromes and genetics. Journal of Neurology, Neurosurgery, and Psychiatry. 2003;74:192–7.
  8. Price SA and Wilson LM. Patofisiologi: Konsep klinis proses-proses penyakit. 6th ed. Translated from English by B.U. Pendit et al. Jakarta: EGC. 2005.
  9. Greener M. Beyond seizures: Understanding cognitive deficits in epilepsy. Progress in Neurology and Psychiatry. 2013;(June):31–2.
  10. Agrell B, Dehlin O. The clock-drawing test. Age Agein. 1998;27:399–403.
  11. Dahlan MS. Besar sampel dan cara pengambilan sampel dalam penelitian kedokteran dan kesehatan. 3rd ed. Jakarta: Salemba Medika. 2013.
  12. Jayant R, Aashal S,Yadav PP, Chaudhari M. Impact of anti-epileptic drugs on cognition: A review. International Journal of Basic and Clinical Pharmacology. 2016;5(2):229–34.
  13. Sundariyati IGAH, Ratep N, Westa W. Gambaran faktor-faktor yang mempengaruhi status kognitif pada lansia di wilayah kerja Puskesmas Kubu II. E-Jurnal Medika Udayana. 2015;4(1).
  14. Al Rasyid I, Syafrita Y, Sastri S. Hubungan faktor risiko dengan fungsi kognitif pada lanjut usia kecamatan Padang Panjang Timur kota Padang Panjang. Jurnal Kesehatan Andalas. 2017;6(1):49–54.
  15. Kim EH, Ko TS. Cognitive impairment in childhood onset epilepsy: Up to date information about its causes. Korean Journal of Pediatrics. 2016;59(4):155–64.
  16. Vingerhoets G. Cognitive effects of seizures. Seizure. 2006;15(4):221–6.
  17. You SJ. Cognitive function of idiopathic childhood epilepsy. Korean Journal of Pediatrics. 2012;55(5):159–63.
  18. Behavior SS, Motamedi G, Meador K. Behavior. Epilepsy and Behavior. 2003;4:S25–S38.
  19. Carren M, Donaire A, Sa R. Cognitive disorders associated with epilepsy?: Diagnosis and treatment. Neurologist. 2008;14(6S):26–34.
  20. Koleoso ON and Uwadiae E. Intellectual function among epileptic children?: The role of epilepsy related-factors in Nigeria. IOSR-JHSS. 2013; 16(4): 41–6.
  21. Aldenkamp A and Bodde N. Behaviour,cognition and epilepsy. Acta Neurologica Scandinavica. 2005; 112: 19–25.
  22. Mundkur N. Neuroplasticity in children. Indian Journal of Pediatrics 2005; 72: 855–7.
  23. Raymont V, Grafman J, Raymont V and Grafman J. Cognitive neural plasticity during learning and recovery from brain damage. Progress in Brain Study. 2006; 157: 199–205.
  24. Johnston MV. Plasticity in the developing brain: Implications for rehabilitation. Developmental Disabilities Research Reviews. 2009; 15(2): 94–101.
  25. Budde H, Wegner M, Soya H, Voelcker-rehage C and Mcmorris T. Neuroscience of exercise?: Neuroplasticity and its behavioral consequences. Neural Plasticity. 2016: 3–6.
  26. Kolb B and Gibb R. Brain plasticity and behaviour in the beveloping brain. Journal of the Canadian Academy of Child and Adolescent Psychiatry. 2011; 20(4): 265-76.
  27. Kirk V, Fatola C and Gonzalez MR. Systematic seview of mindfulness induced neuroplasticity in adults: Potential areas ofiInterest for the maturing adolescent brain. Journal of Childhood and Developmental Disorders. 2016; 2:1.
  28. Baram TZ. The brain, seizures and epilepsy throughout life: Understanding a moving target. Epilepsy currents. 2012; 12(Suppl 3): 7–12.