Article Sidebar

Submitted
October 25, 2016
Accepted
October 25, 2016
Published
October 25, 2016
Download
PDF
Statistic
Read Counter : 941 Download : 1298

Main Article Content

Abstract

Microwave assisted chitosan synthesis as biodegradable material for biomedical application has been done. The purpose of this research is to synthesis of chitosan with high DD and low molecular weight using microwave energy, the study of reaction conditions include parameters of power and reaction time. Chitosan was prepared by deacetylation of chitin with 60% NaOH solution. Conventional method has been done by reflux for 90
minutes, resulting chitosan with DD of 79.5%, 72.6% yields and molecular weight 6051 g/mol. Green chemistry method using microwave radiation at 800 Watts for 5 minutes has produced chitosan with highest DD, yield and molecular weight of 86%, 75% and 3797 g/mole respectively. Synthesis of Chitosan by microwave radiation method can save 10x electrical energy for the reaction, also rapidly and effectively to produce chitosan with low molecular weight compared to conventional methods

Keywords

Chitin Chitosan Microwave Reaction

Article Details

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
Setyawati, A., Pranowo, D., & Kartini, I. (2016). Green Chemistry: Effect of Microwave Irradiationon Synthesis of Chitosan for Biomedical Grade Applications of Biodegradable Materials. EKSAKTA: Journal of Sciences and Data Analysis, 16(2), 137–148. https://doi.org/10.20885/eksakta.vol16.iss2.art8
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
Crossref
Scopus
Google Scholar
Europe PMC

References

  1. Anonim.2005.Laporan Statistik Perikanan Jawa Timur Tahun 2005. Dinas Kelautan dan Kelautan Jatim. Surabaya: DKP.
  2. Alishahi, A., Mirvaghevi, A., Tehrani, M.R., farahmand, H., Shojaosadati, S.A., Dorkoosh, F.A., dan Elsabee, M.Z., 2011. Enhancement and Characterization of Chitosan Extraction from the Wastes of Shrimp Packaging Plants. J. Polym. Environ. 19. 776-783.
  3. Aranaz, I., Mengibar, M., Harris, R., Panos, I., Miralles, B., Acosta, N., galed, G., and Heras, A., 2009. Funcional Characterization of Chitin and Chitosan.J. Current. Chem. Bio. 3. 203-230.
  4. Emmawati, A., Jenie, B.S.L., dan Fawzya, Y.N., 2007. Kombinasi Perendaman Dalam Natrium Hidroksida dan Aplikasi Kitin Deasetilasi terhadap Kitin Kulit Udang untuk Menghasilkan Kitosan dengan Berat Molekul Rendah, J. Teknologi Pertanian. 3(1). 12-18.
  5. Fajarwati, F.I.,Sugiharto, E., danSiswanta, D., 2016.Film of Chitosan-Carboxymethyl cellulose Poly electrolyte Complex as Methylene Blue Adsorbent. Eksakta.16(1).
  6. Haryani, K.,Hargono, dan C. S. Budiyati. (2007). Pembuatan Khitosan Dari Kulit Udang untuk Mengadsorbsi Logam Krom (Cr6+) dan Tembaga (Cu). Reaktor.11 (2).86 – 90.
  7. Junaidi, A.B., kartini, I., dan Rusdiarso, B., 2009. Preparasi Kitosan Melalui Deasetilasi Kitin Secara Bertahap dan Sifat Fisikokimianya. Indo. J. Chem. 9 (3). 369-372.
  8. Khan, T.A., Peh, K.K., and Cheng, H.S., 2002. Reporting Degree of Deacetylation Values of Chittosan: The Influence of Analytical Methods. J. Pharm. Sci, 5(3). 205-212.
  9. Moreno, A., Hoz, D.L.A., andDi´az-Ortiz, A., 2005. Microwaves inorganic synthesis. Thermal and non-thermal microwave effects.Chem. Soc. Rev., 34. 164–178.
  10. MuzzarelliR.A.A., Rochetti, R., Stanic, V., dan Weckx, M., 1997. Methods for the Determination of the Degree of Acetylation of Chitinand Chitosan, Chitin Handbook. European Chitin Soc.Grottamare.
  11. Patil, R.S., Chormade, V., dan Desphande, M.V., 2000.Chytinolytic Enzymes an Exploration. Enz. Microb. Technol. 26.473-483.
  12. Rahayu, E., 2009. Pengaruh Konsentrasi Kitosan pada Pembuatan Komposit Kitosan Lempung. Skripsi. Jurusan Kimia FMIPA UGM.Yogyakarta.
  13. Sahu, A., Goswami, P., dan Bora, U., 2009. Microwave Mediated Rapid Synthesis of Chitosan. J. Mater.Sci. Lett. 20. 171-175.
  14. Tretenichenko, E.M.; Datsun, V.M.; Ignatyuk, L.N.; Nud’ga, L.A., 2006. Preparation and Properties of Chitin and Chitosan from a Hydroid Polyp. Russ. J. Appl. Chem. 79.1341–1346.
  15. Tsigos, I., Martinou, A., Kafetzopoulos and Bouriotis, V., 2000. Chitin Deacetylases: New Versatile Tools in Biotechnology. J. Tibtech. Rev. 18. 305-312.
  16. Wongpanit, P., Sanchavanakit, N., Pavasant, P., Supaphol, P., Tokura, S., Rujivanit, R., 2011. Preparation and Characterization of Microwave-treated Carboxymethyl Chitin and Carboxymethyl Chitosan Films for Potential Use in Wound Care Application. J. Macromolecule Bioscience. 5.1001-1012.