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Submitted
March 10, 2020
Accepted
January 28, 2021
Published
April 30, 2021
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Abstract

Background: Irregular menstrual cycles are a risk factor for developing type 2 diabetes mellitus (DM) in women.
Objective: This study aimed to evaluate irregular menstrual cycles as a risk factor of type 2 DM in women of childbearing age with body fat percentage, waist-hip ratio, diet quality, and physical activity as confounding factors.
Methods: This was a case-control study. Its subjects were subjects with type 2 diabetes mellitus (n=31) and subjects without any clinical evidence of abnormal glucose regulation (n=31) who attended Puskesmas (Community Health Centre) Rowosari, Tembalang, Semarang with over 30 years of age. Based on their menstrual cycles, they were divided into two groups: women with irregular menstrual cycles, and those with regular menstrual cycles. Cochran Mantel-Haenszel test was used to control their confounding factors.
Results: There was an association between irregular menstrual cycles and type 2 DM (p<0.05) with a 7.2 greater risk on women of childbearing age (OR = 7.2, 95% CI=2.18-23.75). By the Cochran Mantel-Haenszel test, the association was still significant; women with over percentage of body fat and central obese with irregular menstrual cycle had 4,85 times and 4,37 times of sequentially greater risk on type 2 DM (OR = 4.85, 95% CI=0.98-23.95 vs OR = 4.37, 95% CI=0.93-20.51).
Conclusion: The irregular menstrual cycles was a risk factor of type 2 DM, especially in obese women of childbearing age.

Keywords

women of childbearing age irregular menstrual cycles type 2 diabetes mellitus diabetes mellitus tipe 2 siklus menstruasi wanita usia subur

Article Details

Author Biographies

Dhea Aghestya, Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Departemen Ilmu Gizi, Fakultas Kedokteran

Nurmasari Widyastuti, Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Departemen Ilmu Gizi, Fakultas Kedokteran

Martha Ardiaria, Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Departemen Ilmu Gizi, Fakultas Kedokteran

Fillah Fithra Dieny, Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Departemen Ilmu Gizi, Fakultas Kedokteran
How to Cite
Aghestya, D., Widyastuti, N., Ardiaria, M., & Dieny, F. F. (2021). Irregular menstrual cycles as a risk factor of type 2 diabetes mellitus in women of childbearing age. JKKI : Jurnal Kedokteran Dan Kesehatan Indonesia, 12(1), 19–27. https://doi.org/10.20885/JKKI.Vol12.Iss1.art5
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